关键词: 结核/治疗, HIV感染, 重叠感染, 病人医护管理, 广东省

Abstract: Objective To analysis the present management of the HIV positive tuberculosis patients in key districts of Mtb and HIV co-infection control in Guangdong, and to provide reference for co-infection control improvement.  Methods The registration, treatment management and effect of the 103 HIV positive tuberculosis cases registered from January 2012 to June 2013 in 11 key Mtb and HIV co-infection control districts in Guangdong were analyzed with retrospective methods.  Results “Cough, expectoration for more than 2 weeks” occurred in 85.4% (88/103) of the HIV positive tuberculosis patients. Most patients (91.3%, 94/103) had typical chest X ray of tuberculosis showing patchy and cord sign. Only 45.6% (47/103) of the patients had confirmed record of ART and 41.7% (43/103) had definite CD4⁺ T lymphocyte counts. One patient refused the treatment for certain reason and more than half (53.9%, 55/102) of the patients received DOT for the whole treatment. The treatment success rates of new smear positive and new smear negative cases were 87.8% (36/41) and 87.9% (51/58) respectively, and 2 out of 3 retreatment cases were cured. Four new smear positive cases and 3 new smear negative cases dead.  Conclusion Although certain achievements have been made for HIV positive tuberculosis cases management in the Mtb and HIV co-infection key districts of Guangdong, the integration of anti-TB chemotherapy and ART, and reducing the mortality still need to be further strengthened.

Key words: Tuberculosis/therapy, HIV infections, Superinfection, Patient care management, Guangdong province